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[1][2][3] by blocking telomerase activity, imetelstat causes telomere shortening, inhibits the proliferation of malignant stem and progenitor cells and induces cell death. This medicine is to be given only by or under the immediate supervision of your doctor. Imetelstat is a first‐in‐class oligonucleotide competitive inhibitor of human telomerase enzymatic activity that leads to the loss of a cancer cell's ability to maintain tl, resulting in the inhibition of cell proliferation. Rytelo (imetelstat) is a medicine used to treat myelodysplastic syndromes (mds)
Mds is a rare group of disorders that affect your blood cells Most people who get mds are 65 years of age or older. Imetelstat sodium works by blocking the activity of an enzyme called telomerase, which is found at high levels in cells that divide rapidly, including cancer cells Blocking this enzyme keeps cancer cells from dividing and causes them to die
Imetelstat is in a class of medications called telomerase inhibitors It works by stopping the production of unhealthy red blood cells.
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